- Product Details
Keywords
- Rafoxanide
- Pharmaceutical Intermediates
- Rafoxanidum
Quick Details
- ProName: Top Quality 99% Rafoxanide BPV85 CAS.2...
- CasNo: 22662-39-1
- Molecular Formula: C19H11Cl2I2NO3
- Appearance: Greyish white to brown powder
- Application: pharmaceutial immediate
- DeliveryTime: 3-7 days
- PackAge: Double plastic bag inside, aluminum fo...
- ProductionCapacity: 10 Metric Ton/Day
- Purity: 99%min
- Storage: Stored in a clean, cool, dry area; kee...
- Transportation: By sea, air, TNT, Fedex, DHL or other ...
- LimitNum: 1 Kilogram
Superiority
1. Mixed container, we can mix different items in one container.
2. Quality control, GC&HPLC&NMR Test.
3. Prompt shipment with professional documents.
4. Packing as your request, with photos before shipment.
5. High quality and competitive price
Details
Description:
Rafoxanide supplier
CAS NO 22662-39-1
Assay 99% min
Specification BPV85
Rafoxanide with good quality
Specifications:
TEST ITEMS |
STANDARD PRESCRIBE |
TEST RESUET |
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Appearance
|
Greyish white to brown powder |
Almost white powder |
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Identification |
IR |
Creyish white to brown powder |
Complies |
||
UV |
Maxinum absorption wavelngth at280 nm;about0.97 Maximun absorption wavelength at 335 nm;about 0.59 |
Complies |
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Melting point |
About 175°C |
176-177°C |
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Assay |
98.0%-101.0% Calculated on the dry bass |
99.5% |
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Loss on drying |
≤0.5% |
0.1% |
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TLC Related substances |
Total impuntles: ≤1.0% Individual specifled impurity: ≤0.5% Not more than 3 impurities equal to or greater than 0.2 Unspecifled impurity: ≤0.2% |
TOTAL:<1.0% Absent 0
|
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Particle size |
95%<45μm |
95%<27μm |
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Residual sovent |
Metanol: ≤1000ppm Toluene: ≤890ppm Acetone: ≤1000ppm |
Metanol:33ppm Toluene:6ppm Acetone:218ppm |
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Conclusion |
The product meets the specification of BPV 85 |
Application:
- Rafoxanide is a halogenated salicylanilide.
- It is an uncoupler of the mitochondrial oxidative phosphorylation resulting in inhibition of the ATP-synthesis.
- This induces a dramatic change in the energy metabolism which finally leads to the death of the parasite.
- It binds more strongly to blood proteins, and therefore remain in the blood for longer periods.
- Rafoxanide is active mainly against adult stages of liver flukes in cattle, sheep, goats and horses.
- It has lower efficacy against immature flukes may be due to the high protein binding of the drug in the blood.
- But it has high activity against 6-wk-old flukes in cattle and sheep, by affecting them either at the time of administration or, more probably, by persisting in blood until the flukes start to ingest blood and become exposed to higher drug concentrations.
- It is also active against gastrointestinal nematodes (Haemonchus, Bunostomum, Oesophagostomum and Gaigeria species) and against the sheep nasal bot fly (Oestrus ovis).
Packaging & Shipping:
Package: Double plastic bag inside, aluminum foil bag or fiber drum outside.
Delivery Detail: Within one week
Storage: Stored in a clean, cool, dry area; keep away from strong, direct light.
Shelf Life: Two years when properly stored.
About Us:
Changzhou Greater Asia Pacific Trading Co., Ltd is a HongKong fully owned enterprise in China that is engaged in supplying the cosmetic/food ingredients with best quality in China. China is a resourceful country for natural plants and herbs. With China industrialization gets better and better, we have the best plant extracts and herb extracts in the world with the most reasonable prices.
We are a supplier of cosmetic ingredients/food ingredients including plant extracts, natural cosmetic ingredients.
We have strong and stable supply networks all over the country and we do business with customers in Europe, Asia and America.
We strive to identify, develop and supply Ingredients from Botanicals/Herbs, for the usage in beverage, health food, cosmetic and pharmaceutical industries, making contributions to the modernization and internationalization of Chinese Herb Medicines and human health. We only supply products manufactured and packaged in accordance with GMP standards.